Compared with the baselines of the addional risk factors of INSIGHT and ALLHAT were not much different. In generally, our summation of risk factors was similar with the developed countries. The proportion of the family history of CVD was lower than in the INSIGHT (5.2 vs. 20) and the proportion of hypercholesterolemia was also lower than in both INSIGHT and ALLHAT. May these differences explain for the difference of the incidence of cardiovascular mortality due to stroke higher than heart disease in Vietnam as well as in the South East ASIA?. This problem requires to study thoroughly in the future. However, if total cholesterol level is over 2 gel, the proportion of hypercholesterolemia would be 49 %. For the proportion of HDL-C < 35 mg/dl was 51%, which according to the ATP III, HDL-C < 40 mg/dl is as the major independent risk factors and the Heart Protection Study noted that the treat with statin even the subjects with LDL-C level < 100mg/dl have also decreased significant for the cardiovascular mortality. Therefore, we must pay on more attention on these major risk factors in the hypertensive patients. For type II diabetes is now considered as a cardiovascular disease more than a metabolic disease, the proportion of diabetes coexists with hypertension was similar with the developed countries. Nowadays, ATP III raised persons with diabetes but without CHD to the risk level of CHD risk equivalent. Both JNC VI and 1999 WHO/ISH placed the hypertensive patients who have diabetes into the very high-risk group with the goal of treatment is < 130/85 mmHg. In Europe and Canada, the current recommendations for the diabetic patients without nephropathy are that BP be reduced to = 130/80 mmHg and that DBP of 80 mmHg is safe.