RESULTS

The baseline characteristics of men and women in the study are presented in the Table 3. The ratio of male/female was 1.18. The mean age was 71 years (range 64-78 years). The prevalence of ISH was 36.04 %( Figure 1).The mean summation of major risk factors per individual was 1.5 ± 0.82 with 1.89 ± 0.81 in male and 1.05 ±0.58 in female (P<0.001). The percentage of additional risk factors included: Hypercholesterolemia (>2 g/l): 49.41 % (>2.5g/l: 10.89%), Smoking: 29.45 %, Diabetes mellitus: 21.17%, Family history of premature CVD: 5.81 %, HDL-C < 35mg/dl: 51.51 %, LDL -C >130mg/dl: 46.66%, Obesity: 1.62 %. Overweight: 12.60 %, Left ventricular hypertrophy: 18.29 %, Microalbuminuria /diabetes: 25.92 %, Cerebrovascular disease: 10.07 %, Heart disease: 11.62 %, Renal disease: 3.48 % (Figure 2), and Hypertension with grade 1: 35.82 %, grade 2: 42.63 %, grade 3: 20.54 % (Figure 3).

Table2. Some baseline characteristics of hypertensive patients between men and women

 

Mean ± STD

Male ± STD

Female±  STD

Value  P

 

Age

71.89 ±7.69

70.87±6.72

71.56±8.08

0,456

 

Weight (kg)

52.86 ± 10.61

56.84±10.14

48.29±9.23

0.0001

Height (m)

1.56 ± 0.07

1.61±0.05

1.51±0.05

0.0001

 

BMI

21.46± 4.75

21.79±3.41

21.08±3.99

0.13

 

Systolic (mmHg)

164.69±17.20

166.37±16.86

162±17.47

0.08

 

Diastolic (mmHg)

90.58±9.19

92.03±9.07

88.85±9.06

0.005

 

Mean BP (mmHg)

115.28±10.24

116.81±9.73

113.47±10.57

0.009

 

Total cholesterol (mg/dl)

202.18±45.06

213.64±51.19

188.68±31.80

0.0001

 

Glucose  (mg/dl)

LDL-Cholesterol (mg/dl)

113.92±49.6

125.93 ±37.2

108.81±36.69

133.87±42.9

120.05±61.24

122.71±34.2

0.07

0.92

 

HDL-Cholesterol (mg/dl)

37.78±19.93

40.81±15.75

36.55±21.34

1.96

 

Triglyceride (mg/dl)

175.80±110.67

169.71±121.10

182.84±97.30

0.34

 

Mean risk factor number

1.5±0.82

1.89±0.81

1.05±0.58

0.0001

 

Mean hypertension grade

1,83±0.74

1.87±0.69

1.79±0.79

0.42

 

Mean risk group

3.06±0.90

3.04±0.87

3.08±0.94

0.76

 



There was a negative correlation between the BMI with the age r (2): -2.38 P<0.01. There was no correlation between the summations of risk factors with the mean BP. (Figure 4). The rate of stratifying risk to quantify prognosis (of the typical 10-year risk of stroke or myocardial infarction) with "Low risk": 2.32 %, "Medium risk": 39.62 %, "High risk": 25.96 %, " Very high risk": 41.08 % (Figure 5). The application of the current guidelines for medical practitioners at local was very modest. Most of hypertensive patients were not assessed about for risk stratification. The proportions of the drug use were seen in Figure 6. There was no large difference when compared with the patient population of the INSIGHT and ALLHAT trials (Figure 7). The proportions of patients with one, two, three and more additional risk factors were 54 %, 36 %, 7 % and 2% respectively (Figure 8).